EDC

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EDC Specification

Storage Instructions
Store in a cool dry place away from moisture

Solubility
Freely soluble in water

Molecular Weight
191.64 g/mol (approximate based on structure shared)

Appearance
Solid crystalline powder

Odour
Odourless

Chemical Name
EDC Hydrochloride

Other Names
Ethyl(dimethylaminopropyl)carbodiimide hydrochloride

Classification
Coupling agent in peptide synthesis

Type
Chemical reagent

Application
Pharmaceutical intermediates and chemical synthesis

Application Method
Used in controlled reactions and formulations

Raw Material
Organic chemicals

Physical State
Solid

Usage
Used in peptide synthesis and chemical modifications

Shelf Life
24 months

Best Before
24 months from the date of manufacture

About EDC

3-(3-dimethylaminopropyl)carbodiimide (EDC, EDAC or EDCI) is a water-soluble carbodiimide usually obtained as the hydrochloride. It is typically employed in the 4.0-6.0 pH range. It is generally used as a carboxyl activating agent for the coupling of primary amines to yield amide bonds. Additionally, EDC can also be used to activate phosphate groups in order to form phosphomono-esters and phosphodiesters. Common uses for this carbodiimide include peptide synthesis, protein crosslinking to nucleic acids, but also in the preparation of immunoconjugates. EDC is often used in combination with N-hydroxysuccinimide (NHS) for the immobilisation of large biomolecules.

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